Disruption of CTCF at the miR-125b1 locus in gynecological cancers
نویسندگان
چکیده
منابع مشابه
Disruption of CTCF at the miR-125b1 locus in gynecological cancers and breast cancer cell lines
Background In cancer cells, transcriptional gene silencing has been associated with genetic and epigenetic defects. The disruption of DNA methylation patterns and covalent histone marks has been associated with cancer development. In non-neoplastic cells the multifunctional CCCTC-binding factor (CTCF) can serve as a barrier against the spread of DNA methylation and histone repressive marks into...
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The value of lateral lymphoscintigraphy images of the pelvis for gynecological cancers: Are they necessary?
Introduction: In the current study we evaluated the incremental value of lateral pelvic lymphoscintigraphy imaging of endometrial or cervical cancer patients who underwent sentinel node mapping. Methods: Operable endometrial and cervical cancer patients without clinical or paraclinical evidence of lymph node involvement were included in the study. The day before surgery the patients were sent ...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2012
ISSN: 1471-2407
DOI: 10.1186/1471-2407-12-40